In the movie, James is busy testing his brain pills on our genetic neighbors, explaining: "Our drug allows the brain to repair itself. We call it... the cure." Oh the hubris!
By the time he realizes they're making the apes so smart that they're dangerous, well it's already too late. San Francisco becomes a battleground for the war against the apes and we imagine in a few years time the super-smart grunts will have figured out how to topple the Statue of Liberty. Check out the trailer for some ape-on-Franco action.